Faculty Publications and Patents
High Impact Publications
Dr. Hiranmoy Das, Professor in the Pharmaceutical Sciences Department, and his laboratory
recently published, "KLF2 regulates dental pulp-derived stem cell differentiation
through the induction of mitophagy and altering mitochondrial metabolismā. To define
the regulatory role of Kruppel-like factor 2 (KLF2) during osteoblast (OB) differentiation
of dental pulp-derived stem cell (DPSC)s, herein, we show that the levels of KLF2
and autophagy-related molecules were significantly increased in differentiated cells.
Gain-of-function and loss-of-function approaches of KLF2 confirmed that KLF2 modulated
autophagic and OB differentiation-related molecules. In addition ... (READ ARTICLE)
(Impact Factor: 9.986)
Faculty Publications
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- Rashdan S, Yang H, Le T, Selby C, Gerber DE, Alvarez CA. Prevalence and Significance
of Potential Pharmacokinetic Drug-Drug Interactions Among Patients with Lung Cancer:
Implications for Clinical Trials. Clin Drug Investig. 2021 Jan 8. doi: 10.1007/s40261-020-00994-4.
Online ahead of print.
PMID: 33417195
- L. Parker Gregg, S. Susan Hedayati, Hui Yang, Peter N. Van Buren, Subhash Banerjee, Sankar D. Navaneethan, Salim S. Virani, Wolfgang C. Winkelmayer, Carlos A. Alvarez. Association of Blood Pressure Variability and Diuretics With Cardiovascular Events in Patients With Chronic Kidney Disease Stages 1ā5. Hypertension, vol. 77, No. 3, 948-959, 11 Jan 2021.
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Lee P, Fike D, Yang H, Hall RG 2nd, Pass S, Alvarez CA. Do the types and routes of proton pump inhibitor treatments affect Clostridium difficile in ICU patients?: A retrospective cohort study. Expert Rev Clin Pharmacol. 2021 Feb 12. doi: 10.1080/17512433.2021.1890582. Online ahead of print.PMID: 33576287
- Mansi IA, Chansard M, Lingvay I, Zhang S, Halm EA, et al. (2022) Statins and renal disease progression, ophthalmic manifestations, and neurological manifestations in veterans with diabetes: A retrospective cohort study. PLOS ONE 17(7): e0269982.
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- Bailey T, and Terrell B. Geriatric Syndromes in Ambulatory Care In: Irons BK, Meredith AH, eds. Ambulatory Care Self-Assessment Program, 2023 Book 2. Geriatric and Pediatric Care. Lenexa, KS: American College of Clinical Pharmacy, 2023
- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. https://doi.org/10.1016/j.cptl.2022.07.037.
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- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. https://doi.org/10.1016/j.cptl.2022.07.037.
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- Levi S. Campbell, Tiffany N. Coomer, George K.Jacob, Ranee J. Lenz. Gabapentin controlled substance status. Journal of the American Pharmacists Association. J Am Pharm Assoc (2003). 2021 Mar 2;S1544-3191(21)00027-3. doi: 10.1016/j.japh.2021.01.025. Online ahead of print.
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- Levi S. Campbell, Tiffany N. Coomer, George K.Jacob, Ranee J. Lenz. Gabapentin controlled substance status. Journal of the American Pharmacists Association. J Am Pharm Assoc (2003). 2021 Mar 2;S1544-3191(21)00027-3. doi: 10.1016/j.japh.2021.01.025. Online ahead of print.
- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. .
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- Rush SW, Chain JL, and Das H. Corneal epithelial stem cell supernatant in the treatment of severe dry eye disease: a pilot study. Clinical Ophthalmology- 16 July 2021 Volume 2021:15 Pages 3097-3107. DOI .
- Deb M, Laha D, Maity J, and Das H. SETD2-mediated epigenetic regulation of noncanonical Wnt5A during osteoclastogenesis. Clinical Epigenetics- In Press, 2021.
- Klionsky DJ,ā¦.. Das Hā¦ā¦et al. Guidelines for the use and interpretation of assays
for monitoring autophagy (4th edition), Autophagy, 2021. DOI: 10.1080/15548627.2020.1797280;
.
(IF: 16.016) - Kanji S, Greene CJ, and Das H. Dental pulp-derived stem cells inhibit osteoclast differentiation
by secreting osteoprotegerin and deactivating AKT signaling in monocytes. Journal
of Cellular and Molecular Medicine. 2021 Jan 28. doi: 10.1111/jcmm.16071.
(IF: 5.310)
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- Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2021 Jan 1;209:112866. doi: 10.1016/j.ejmech.2020.112866. Epub 2020 Sep 24.PMID: 33039722
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- Lee P, Fike D, Yang H, Hall RG 2nd, Pass S, Alvarez CA. Do the types and routes of
proton pump inhibitor treatments affect Clostridium difficile in ICU patients?: A
retrospective cohort study. Expert Rev Clin Pharmacol. 2021 Feb 12. doi: 10.1080/17512433.2021.1890582.
Online ahead of print.
PMID: 33576287
- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. .
Link to Publications: Click
- Levi S. Campbell, Tiffany N. Coomer, George K. Jacob, Ranee J. Lenz. Gabapentin controlled substance status. Journal of the American Pharmacists Association. J Am Pharm Assoc (2003). 2021 Mar 2;S1544-3191(21)00027-3. doi: 10.1016/j.japh.2021.01.025. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/33674205/
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- Joshua Day, MBA, Pharm.D. Candidate; Dr. Jeanie Jaramillo-Stametz, Pharm.D., MS. Impact of the COVID-19 Pandemic on Suspected Attempted Suicides (especially in chilĀdren) and Exposures to Selected Substances Used to āPreventā or āTreatā COVID-19. TPHA Journal 2021;73(2):4-7
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- Rogers SL, Patrinos GP, Mitropoulou C, Formea CM, Jones JS, Brown BG. Inaugural Pharmacogenomics Access and Reimbursement Symposium. Pharmacogenomics. 2021 Jun;22(9):515-517. doi: 10.2217/pgs-2021-0016. Epub 2021 May 25.PMID: 34032472
- Rogers SL, Patrinos GP, Mitropoulou C, Formea CM, Shawn Jones J, Brown BG. Conference report: inaugural Pharmacogenomics Access & Reimbursement Symposium. Pharmacogenomics J. 2021 Jun 17:1-3. doi: 10.1038/s41397-021-00240-w. Online ahead of print.PMID: 34140646
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- Levi S. Campbell, Tiffany N. Coomer, George K. Jacob, Ranee J. Lenz. Gabapentin controlled substance status. Journal of the American Pharmacists Association. J Am Pharm Assoc (2003). 2021 Mar 2;S1544-3191(21)00027-3. doi: 10.1016/j.japh.2021.01.025. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/33674205/
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- Wooster AL, Girgis LH, Brazeale H, Anderson TS, Wood LM, Lowe DB. Dendritic cell vaccine therapy for colorectal cancer. Pharmacol Res. 2021 Feb;164:105374. doi: 10.1016/j.phrs.2020.105374. Epub 2020 Dec 28.PMID: 33348026
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- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. .
Link to Publications: Click
Link to Publications: Click
Link to Publications: Click
- Burton C, Mathys M, Gutierrez E. Comparison of lithium to second generation antipsychotics
for the treatment of bipolar disorder in older veterans. Psychiatry Res. 2021 Jun
17;303:114063. doi: 10.1016/j.psychres.2021.114063. Online ahead of print.
PMID: 34171570
Link to Publications: Click
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- Lee P, Fike D, Yang H, Hall RG 2nd, Pass S, Alvarez CA. Do the types and routes of proton pump inhibitor treatments affect Clostridium difficile in ICU patients?: A retrospective cohort study. Expert Rev Clin Pharmacol. 2021 Feb 12. doi: 10.1080/17512433.2021.1890582. Online ahead of print.PMID: 33576287
- Emily M. Buatois, Adebola A. Akunna, Trista Bailey, Tiffany N. Coomer, William C.
Putnam, Ronald G. Hall, Steven E. Pass, Eric J. MacLaughlin. Using the HyFlex model
to deliver a capstone seminar course.
Currents in Pharmacy Teaching and Learning. 2022. ISSN 1877-1297. .
Link to Publications: Click
Link to Publications: Click
Link to Publications: Click
- Rashdan S, Yang H, Le T, Selby C, Gerber DE, Alvarez CA. Prevalence and Significance of Potential Pharmacokinetic Drug-Drug Interactions Among Patients with Lung Cancer: Implications for Clinical Trials. Clin Drug Investig. 2021 Jan 8. doi: 10.1007/s40261-020-00994-4. Online ahead of print.PMID: 33417195
Link to Publications: Click
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Kling JM, Sleeper R, Chin EL, Rojek MK, McGregor AJ, Richards L, Mitchell AB, Stasiuk C, Templeton K, Prasad J, Pfister S, Newman CB. Sex and Gender Health Educational Tenets: A Report from the 2020 Sex and Gender Health Education Summit. J Women's Health (Larchmt). 2022 Jul;31(7):905-910. doi: 10.1089/jwh.2022.0222. PMID: 35849755.
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- Akwii RG, Sajib MS, Zahra FT, Madala HR, Srivenugopal KS, Mikelis CM. In Vivo Ear Sponge Lymphangiogenesis Assay. Methods Mol Biol. 2021;2193:85-96. doi: 10.1007/978-1-0716-0845-6_9.PMID: 32808261
Link to Publications: Click
- Bailey T, and Terrell B. Geriatric Syndromes in Ambulatory Care In: Irons BK, Meredith AH, eds. Ambulatory Care Self-Assessment Program, 2023 Book 2. Geriatric and Pediatric Care. Lenexa, KS: American College of Clinical Pharmacy, 2023
Link to Publications: Click
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Published Book Chapters/ Editorials/ Commentaries
- Anderson S and Das H. Cutaneous wound generation in diabetic NOD/SCID mice and the use of nanofiber-expanded hematopoietic stem cell therapy. Methods in Molecular Biology: Wound Regeneration. 2021;2193:41-48. doi: 10.1007/978-1-0716-0845-6_5. PubMed PMID: 32808257.
- Barthels D and Das H. Generation of acute hind limb ischemia in NOD/SCID mice and treatment with nanofiber-expanded CD34+ hematopoietic stem cells. Methods in Molecular Biology: Wound Regeneration. 2021;2193:121-128. doi: 10.1007/978-1-0716-0845-6_12. PubMed PMID: 32808264.
- Greene C and Das H. Development of cutaneous wound in diabetic immunocompromised mice and use of dental pulp-derived stem cell product for healing. Methods in Molecular Biology: Wound Regeneration. 2021;2193:23-30. doi: 10.1007/978-1-0716-0845-6_3. PubMed PMID: 32808255.
- Rolph D and Das H. Generation of myocardial ischemic wounds and healing with stem cells. Methods in Molecular Biology: Wound Regeneration. 2021;2193:141-147. doi: 10.1007/978-1-0716-0845-6_14. PubMed PMID: 32808266.
Publication Archives
Patents / Technologies
- # WO 2020/018868 A1 - Corneal epithelial cells and their products for treating corneal diseases. Date: 1.23.2020 (Hiranmoy Das and S.W. Rush)
- #WO 2019 / 241462 A1 - Stem cells for the treatment for conditions and diseases. Date: 12-19-2019 (Hiranmoy Das)
- #US 2019 / 0091310 A - Nonreleased IL-12 for therapy of cancer. Date: 3.28.2019 (S.E. Wright and Hiranmoy Das)
- #62/725444 - Enhancers of Neurolysin Activity (Vardan T. Karamyan, Paul C. Trippier, Thomas J. Abbruscato, David A. Ostrov, Srinidhi Jayaraman)
- #62/670479 - Method of treating cancer with Atpenin A5 derivatives. (Paul C. Trippier and Paul S. Brookes)
- #PCT/US18/42009 - Functionalized Pyridine Carbamates with
Enhanced Neuroprotective Activity (Paul C. Trippier, Nihar Kinarivala and Rose-Mary Boustany) - #WO 2018148721 A1 - Phenylacrylic acid derivatives as highly selective AKR1C3 inhibitors, methods of use and their preparation. (Paul C. Trippier, Kshitij Verma, Tianzhu Zang and Trevor Penning)
- #62/700,639 - Corneal Epithelial Cells and Their Products for Treating Corneal Diseases. (Hiranmoy Das)
- #PCT/US 2018: 60763 - Composition and methods for treating cancer. (Sanjay K. Srivastava)
- #62/532624 - Functionalized Pyridine Carbamates with enhanced neuroprotective activity (Paul C. Trippier)
- #62/458267 - Highly selective AKR1C3 inhibitors and methods of use thereof (Paul C. Trippier)
- #62/422797 - Potent and selective peroxisome proliferator-activated Receptor beta/delta agonists (Paul C. Trippier)
- PCT/US2016 #036002 - Inhibitors of Mcl-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors (Sanjay K. Srivastava)
- WO2015120254 A1 - Disulfiram compositions and treatments for brain tumors (Kalkunte S. Srivenugopal)
- US 62/268,882. - Small molecule allosteric potentiators of peptidase neurolysin (Vardan T. Karamyan)
- #62/172,327 - Inhibitors of Mcl-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors (Sanjay K. Srivastava)
- # 62/189,377 - Formulations of piperlongumine for oral and topical application for prevention and treatment of melanoma (Sanjay K. Srivastava)
- #62026970 - Overcoming Chemotherapeutic Agent Resistance in Cancer by Inhibiting Mcl-1 (Sanjay K. Srivastava)
- US20140134241 A1 - WO2012129520A1 - TCR Mimic Antibodies as Vascular Targeting Tools (John Weidanz & Ulrich Bickel)
- WO2015095002 A1 - CA2932480 A1 - CN105916882AR - Anti-RON Monoclonal Antibodies as a Cytotoxic Drug Delivery System for Targeted Cancer Therapy (Ming-Hai Wang)
- WO2016049453 A1 - Cancer Treatment Utilizing SP-141 to Bind with MDM2 and Act as an Inhibitor of MDM2 Expression (Ruiwen Zhang & Wei Wang)
- WO2014210411 A1 - Histone deacetylase inhibitors and methods of use (Sanjay K. Srivastava)
- #61973672 - Overcoming vemurafenib resistance in metastatic cancers (Sanjay K. Srivastava)
- #62026970 - Overcoming chemotherapeutic agent resistance in cancer by inhibiting Mcl-1 (Sanjay K. Srivastava)
- WO2013067305 A1 - Media compositions for promoting bacterial and fungal growth (Mark Lyte)
- #61840751 - Histone deacetylase inhibitors and methods of use (Sanjay K. Srivastava)
- WO2013/074820 - Immunogenic tumor associated stromal cell antigen peptides and methods of their use. (WJ Storkus, A. Bose, JL Taylor, X Zhao, DB Lowe)
- US20090087517 A1 - WO2007052081 A3 - Bacterial growth enhancer (Mark Lyte)
- US20090118202 A1 - Compositions and methods of treating hypertension with tannin complexes (Thomas Thekkumkara)
- US20140065708 A1 - Antibodies as t cell receptor mimics, methods of production and uses thereof (Jon A. Weidanz)