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The Texas Tech University Health Sciences Center is conducting a research study that will look at whether calcium, vasopressin, or both early in the course of treatment would help severely injured patients that lose a lot of blood survive their injuries.

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) trial will include approximately 1,050 people aged 18 to 90. Patients who have traumatic injuries with loss of blood may be enrolled by participating emergency medical personnel during their transportation to the hospital or after arrival to University Medical Center Hospital.

CAVALIER is an Exception from Informed Consent (EFIC) trial, meaning that, the trial requires performing a potentially life-saving intervention in people who are too injured to give permission. This study will look at treatment for patients who have a traumatic injury and have lost a lot of blood. These patients are too injured to give permission before receiving the study drug. Permission for continued participation will be obtained from patients once they are able, or from their family members, as soon as possible.

For more information about CAVALIER or to complete an anonymous survey on your thoughts about this EFIC study, please go to

This research is supported by DoD contract W81XWH-16-D-0024 W81XWH-22-F-0118. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the Department of the Army, Department of Defense, or the U.S. Government.

More information on Emergency Research and Exception From Informed Consent (EFIC):

Texas Tech University Health Sciences Center is pleased to announce the creation of the Health Disparities Research Program (HDRP). This program will foster and financially support, wherever possible, research projects addressing health disparities in West Texas. HDRP is an initiative under the Clinical Affairs Council to transform health care through innovation and collaboration. Dr. Steven Berk, Executive Vice-President for Clinical Affairs, and chair of the Clinical Affairs Council, has graciously provided start-up funding to support this disparities research initiative. Up to $10,000 can be requested per project. In the first phase HDRP, seed grants will support research projects focusing on health disparities existing in West Texas. Special consideration will be given for cross departments, schools, and campuses teams promoting multidisciplinary collaboration. Interested investigators need to submit a paragraph in a Word document or PDF format describing the proposed study with the following required information: 

1) Name of PI/Co-PI 
2) School(s)/Department(s)/Campus(es) within �㽶ֱ�� represented by those performing the research
3) Brief, 1 to 2 paragraph, description of the disparities research project
4) Database to be used for data source
5) Budget and amount of funding support requested

Note: Six month and one year progress reports will be required for all funded projects. 

Please submit projects and/or questions to John Griswold, MD at john.Griswold@ttuhsc.edu

Congratulations to Mariana Fiori, PhD, CCRC on being presented the 2024 Distinguished Staff Award. Ms. Fiori was nominated by her peers in the Clinical Research Institute for her contributions to the clinical research and the CRI. Great Job Mariana!!