Wyatt Paulishak | Texas Tech University Health Sciences Center

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Wyatt Paulishak

Immunotherapeutics & Biotechnology

paulishak
  • Graduate Student / Research Assistant

Lab Phone: 325-696-0594
E-Mail: wpaulish@ttuhsc.edu
Mail Address: 1718 Pine Street, Suite 1302
Abilene, TX 79601

Biography

Wyatt Paulishak completed his Bachelor of Arts (BA) degree in Biochemistry from Saint Mary’s College of Maryland, Saint Mary’s City, Maryland, in 2016, and his Master of Science (MS) degree in Biochemistry from Indiana University, Bloomington, Indiana, in 2020. Over the next year, he worked at AbbVie Inc. as a Scientist in their bioanalysis department in North Chicago, Illinois. Wyatt joined the Graduate Program in Pharmaceutical Sciences as a Doctor of Philosophy (PhD) student in August of 2021, and is presently working in the laboratory of Dr. Laurence Wood with the Department of Immunotherapeutics and Biotechnology on our Abilene campus.

Education:

  • MS: Biochemistry, Indiana University, Bloomington, Indiana, 2020
  • BA: Biochemistry, Saint Mary’s College of Maryland, Saint Mary’s City, Maryland, 2016

Research Interests:

Development of novel therapeutic approaches using Listeria monocytogenes as a therapeutic delivery vehicle for the treatment of cancer.

Publications:

  • Nguyen HM, Paulishak W, Oladejo M, Wood L. Dynamic tumor microenvironment, molecular heterogeneity, and distinct immunologic portrait of triple-negative breast cancer: an impact on classification and treatment approaches. Breast Cancer. 2023 Mar; 30(2):167-186. Epub Nov 18.
  • Nguyen HM, Gaikwad S, Oladejo M, Paulishak W, Wood LM. Targeting Ubiquitin-like Protein, ISG15, as a Novel Tumor Associated Antigen in Colorectal Cancer. Cancers (Basel). 2023 Feb 15; 15(4):1237.
  • Oladejo M, Paulishak W, Wood L. Synergistic potential of immune checkpoint inhibitors and therapeutic cancer vaccines. Semin Cancer Biol. 2023 Jan; 88:81-95. Epub 2022 Dec 13.
  • Oladejo M, Nguyen HM, Silwal A, Reese B, Paulishak W, Markiewski MM, Wood LM. Listeria-based immunotherapy directed against CD105 exerts anti-angiogenic and anti-tumor efficacy in renal cell carcinoma. Front Immunol. 2022 Nov 11; 13:1038807.

Presentations:

  • Wyatt E. Paulishak, Laurence M. Wood. "Listeria monocytogenes as a Chemotherapeutic Delivery Vehicle Invades and Kills J774 Cells in vitro in a Payload Dependent Manner". 35th Annual Student Research Week, Ï㽶ֱ²¥ Graduate School of Biomedical Sciences, Lubbock, Feb/Mar 2023.

Seminars:

  • 04/14/2023 "Listeria-Mediated Chemotherapeutic Delivery, a Novel Therapeutic Approach to Cancer Therapy"

Awards/Scholarships:

   Before Admission to GPPS:

  • Geneva Boone Award for Outstanding Saint Mary’s Project, Saint Mary’s College of Maryland, Saint Mary’s City, Maryland, 2016.
  • Bachelors Certification, American Society for Biochemistry and Molecular Biology, 2016.

Memberships:

  • American Society for Biochemistry and Molecular Biology (ASBMB), 2012-2017.
  • American Chemical Society (ACS), 2012-2016.