Ï㽶ֱ²¥

Presentation Calendar

• August 27, 2021 | Rainier Alvir
  Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
• July 30, 2021 | P. Hemachandra Reddy, Ph.D. and Razelle Alvir
  Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study
• June 18, 2021 | P. Hemachandra Reddy, Ph.D.
  Neurovascular Coupling and Oxygenation Are Decreased in Hippocampus Compared to Neocortex Because of Microvascular Differences
• May 28, 2021 | P. Hemachandra Reddy, Ph.D.
  Article 1: Relationship Between Elevated Impulsivity and Cognitive Declines in Elderly Community‑dwelling Individuals
  &
  Article 2: Is the Montreal Cognitive Assessment (MoCA) Screening Superior to the Mini-Mental State Examination (MMSE) in the Detection of Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) in the Elderly?
• April 30, 2021 | P. Hemachandra Reddy, Ph.D.
  Generation of a Humanized Abeta Expressing Mouse Demonstrating Alzheimer’s Disease Like Pathology
• March 26, 2021 | P. Hemachandra Reddy, Ph.D. and Hallie Morton
  Molecular Characterization of Selectively Vulnerable Neurons in Alzheimer's Disease
• November 20, 2020 | Bhagavathi Ramasubramanian, Ph.D.
  Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline
• October 30, 2020 | P. Hemachandra Reddy, Ph.D.
  Mitophagy Alterations in Alzheimer’s Disease are Associated with Granular Vascular Degeneration and Early Tau Pathology
• August 28, 2020 | Tanisha Basu
  Anticipating and Mitigating the Impact of COVID-19 Pandemic on Alzheimer's Disease and Related Dementias
  &
  Caloric Intake, Dietary Lifestyles, Macronutrient Composition, and Alzheimer's Disease Dementia
• August 7, 2020 | Bhagavathi Ramasubramanian, Ph.D.
  Premature Synaptic Mitochondrial Dysfunction in the Hippocampus During Aging Contributes to Memory Loss
• March 2020 | P. Hemachandra Reddy, Ph.D.
  Lifestyle and Alzheimer’s Disease: The Role of Environmental Factors in Disease Development
• February 26, 2020 | P. Hemachandra Reddy, Ph.D.
  Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
• January 29, 2020 | P. Hemachandra Reddy, Ph.D.
  Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca2+ efflux and Reactive Oxygen Species (ROS) homeostasis
• January 22, 2019  |  Neha Sawant
  GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington’s disease: involvement of astrocyte–neuron interactions.
• December 17, 2018  |  Kevin Bass
  Somatic APP gene recombination in Alzheimer’s disease and normal neurons
• November 27, 2018  |  Divya Burugu
  Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents.
• October 23, 2018  |  Darryll Oliver
  First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics.
• September 25, 2018  |  Murali Vijayan, Ph.D.
  MicroRNA-1906, a Novel Regulator of Toll-Like Receptor 4, Ameliorates Ischemic Injury after Experimental Stroke in Mice.
• August 28, 2018  |  Kevin Bass
  Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress.
  
• July 24, 2018  |  Josh Willms
  AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
• June 26, 2018  |  N Bhagavathi Ramasubramanian, Ph.D.
  Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetics failure and cognitive decline in Alzheimer’s disease.
• May 22, 2018  |  C. Breann Williams
  Actin, spectrin and associated proteins form a periodic cytoskeletal structure in axons.
• April 23, 2018  |  Kandi Quesada
  Caring for Parents with Alzheimer’s: A Resource and Guidebook.
• March 27, 2018  |  Kevin Bass
  Ab Secretin and Plaque Formation Depend on Autophagy.
• February 27, 2018  |  Subodh Kumar, Ph.D.
  MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPKPGC1a signaling network.
• November 28, 2017  |  P. Hemachandra Reddy, Ph.D.
  PINK1 signaling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease.
• October 24, 2017  |  John Lawrence, Ph.D.
  Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells.
• September 26, 2017  |  John Lawrence, Ph.D.
  Differential presynaptic ATP supply for basal and high-demand transmission.
• August 22, 2017  |  P. Hemachandra Reddy, Ph.D.
  Hypothalamic stem cells control aging speed partly through exosomal miRNAs.
• July 25, 2017  |  Jake S. Smith, Dr. Subodh Kumar, Dr. Murali Vijayan
  Direct Conversion of Normal Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules.
• June 27, 2017  |  Rui Wang, Ph.D.
  Dopamine Neuronal Loss Contributes to Memory and Reward Dysfunction in a Model of Alzheimer's Disease.
• May 23, 2017  |  P. Hemachandra Reddy, Ph.D.
  Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects Against Adiposity and Insulin Resistance in Mice.
• April 25, 2017  |  Maria Manczak, Ph.D.
  Amyloid ß-peptides interfere with mitochondrial pre protein import competence by congregation process.
• March 28, 2017  |  Murali Vijayan, Ph.D.
  MicroRNA-103-1 Selectively Downregulates Brain NCX1 and its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits.
• February 28, 2017  |  Chandra Sekhar Kuruva, Ph.D.
  Determinants of amyloid fibril degradation by the PDZ protease HTRA1.
• January 24, 2017  |  Jasvinder Bhatti, Ph.D.
  Genetic Analysis of a New Mouse Model for Non-Insulin Dependent Diabetes.
• December 20, 2016  |  J.A. Pradeepkiran, Ph.D.
  In Silico Modeling of Novel Drug Ligands for Treatment of Concussion Associated Tauopathy.
• November 12, 2016  |  Rui Wang, Ph.D.
  Dysfunction of Somatostatin-Positive Interneurons Associated with Memory Deficits in an Alzheimer's Disease Model.
• October 25, 2016  |  Chandra Sekhar Kuruva, Ph.D.
  Tau-Derived Hexapeptide 306VQIVYK311 Aggregation Inhibitors: Nitrocatechol Moiety as A Pharmacoperone in Drug Design.
• September 27, 2016  |  Jasvinder Bhatti, Ph.D.
  Time Restricted Feeding Is a Preventative and Therapeutic Intervention.
• August 30, 2016  |  Linda Yin
  Meta-Analysis of Peripheral Blood Apolipoprotein E Levels in Alzheimer’s Disease.
• July 26, 2016  |  Ramesh Kandimalla, Ph.D.
  Silencing of CDK5 Reduces Neurofibrillary Tangles in Transgenic Alzheimer’s Mice.
• June 28, 2016  |  Subodh Kumar, Ph.D.
  microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.
• May 31, 2016  |  John Lawrence, Ph.D.
  Accelerated aging of the GABAergic septohippocampal pathway and decreased hippocampal rhythms in a mouse model of Alzheimer’s Disease.
• April 26, 2016  |  Murali Vijayan, Ph.D.
  Selective astrocytic endothelin-1 overexpression contributes to dementia associated ischemic stroke by exaggerating astrocyte-derived amyloid secretion.
• March 29, 2016  |  Rui Wang, Ph.D.
  Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.
• February 23, 2016  |  Chandra Sekhar Kuruva, Ph.D.
  Multi-target Drug Discovery for Alzheimer’s Disease: Triazinones as BACE-1 and GSK-3b Inhibitors.
• January 26, 2016  |  Subodh Kumar, Ph.D.
  Genome-Wide Serum microRNA Expression Profiling Identifies Serum Biomarkers for Alzheimer’s Disease.